In recent years, research has shown the involvement of free radicals in the development of the pain that accompanies many pathological conditions. In the treatment of acute and chronic pain, the most effective therapies are natural and synthetic opioid alkaloids. Their metabolism in itself may contribute to the formation of free radicals and thus affect … Read more
Opioid treatment is now an integral part of pharmacotherapy for severe chronic malignant and non-malignant pain. Currently, there is a sufficient selection of opioids to allow individualized pain treatment. Several experimental studies have confirmed the effect of opioids on oxidative stress. The aim of this work is to determine the presence of redox changes occurring … Read more
Pain is the most common symptom linked to oncological illnesses. It has a negative impact on the course of the illness and it significantly decreases the patient‘s quality of life. The neurophysiology of oncological pain is very complex. It involves inflammatory, neuropathic, ischemic and compression mechanisms commonly acting synergistically. The knowledge of these mechanisms and … Read more
RETROSPECTIVE MULTICENTRE OBSERVATIONAL STUDY Epiduroscopy is a percutaneous endoscopic technique with an interesting diagnostic and therapeutic potential. The study was aimed to evaluate the effectiveness of this modern minimally invasive method in treating pain together with the accompanying neurological symptoms of patients with a failed back surgery syndrome (FBSS).
Prospective observational multicentre two-arm parallel study describing clinical outcome after endoscopic discectomy provided via transforaminal and interlaminar approach.
Prospective observational multicentre two-arm parallel study describing clinical outcome after endoscopic discectomy provided via transforaminal and interlaminar approach.
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